一、个人简介
谢卫青,教授、博导。国家自然科学基金优秀青年基金获得者(2017)。2002年毕业于兰州大学,获理学学士学,指导老师陈宝华教授。2007年于必赢线路检测3003上海有机化学研究所获得博士学位,导师马大为研究员。2009-2011年在必赢线路检测3003上海有机化学研究所,任助理研究员。2009年赴美国西南医学中心开展博士后研究工作。2011年重新回到必赢线路检测3003上海有机化学研究所任副研究员。2015年作为青年英才引入必赢线路检测3003,任教授、博士生导师。以通讯作者身份在Angew. Chem., Int. Ed.、Chem. Sci.、Org. Lett.、Chem. Commun.等SCI收录的国际学术期刊上发表论文近二十余篇。
二、科研课题
自然科学基金优秀青年基金(2018年-2020年,130万元);
自然科学基金面上基金(2017年-2020年,65万元);
必赢线路检测3003卓越人才计划(2016年-2019年,70万元);
必赢线路检测3003人才启动经费(2015年-2019年,80万元);
自然科学基金面上基金(2014年-2017年,80万元);
自然科学基金青年基金(2013年-2015年,25万元)。
三、研究领域
目前主要研究方向为有机小分子催化不对称反应及其在天然产物全合成中的应用、具有重要生理复杂活性天然产物合成、基于天然产物的化学生物学研究。
四、开设课程
《有机化学》、《有机合成进展》
五、主要科研成果与学术论文
1. Highly Enantioselective Tandem Michael Addition of Tryptamine-Derived Oxindoles to Alkynones: Concise Synthesis of Strychnos Alkaloids, Weigang He, Jiadong Hu, Pengyan Wang, Le Chen, Kai Ji, Siyu Yang, Yin Li, Zhilong Xie and Weiqing Xie*, Angew. Chem. Int. Ed., 2018, 57, DOI: 10.1002/anie.201800567
2. New Strategy for Forging Contiguous Quaternary Carbon Centers via H2O2-Mediated Ring Contraction, Jiadong Hua , Xin Yu, Weiqing Xie*, Synlett. 2017, 28, 2517-2524.
3. Facile Access to 2,2-Disubstituted Indolin-3-ones via Cascade Fischer Indolization/Claisen Rearrangement Reaction, Zilei Xia, Jiadong Hu, Yu-Qi Gao, Qizheng Yao,* Weiqing Xie,* Chem. Commun., 2017, 53,7485-7488.
4. A Re2O7 catalyzed cycloetherification of monoallylic diols, Xiaolong Wan, Jiadong Hu, Dongyang Xu, Yang Shang, Yanxia Zhen, Chenchen Hu, Fan Xiao, Yu-Peng He,* Yisheng Lai, * Weiqing Xie, * Tetrahedron Lett. 2017, 58, 1090–1093.
5. Stereospecific Construction of Contiguous Quaternary All-Carbon Centers by Oxidative Ring Contraction. Xin Yu+, Jiadong Hu+, Zhigao Shen, Hui Zhang, Jin-Ming Gao, and Weiqing Xie*. Angew. Chem. Int. Ed., 2017, 56, 350–353.
6. Tandem allylic alcohol isomerization/oxo-Michael addition reaction promoted by Re2O7. Jiadong Hu, Dongyang Xu, Qiang Zhang, Yang Shang, Mumin Shi, Yucui Huangfu, Leilei Liu, Rong liang, Yisheng Lai,* Yupeng He,* Jin-ming Gao and Weiqing Xie*, RSC Adv. 2016, 6, 52583–52586.
7. Enantioselective Bromo-oxycyclization of Silanol, Zilei Xia, Jiadong Hu, Zhigao Shen, Xiaolong Wan, Qizheng Yao, Yisheng Lai, Jin-Ming Gao, Weiqing Xie*, Org. Lett. 2016, 18, 80–83.
8. Chiral Ion-Pair Organocatalyst Promotes Highly Enantioselective 3-exo Iodo-cycloetherification of Allyl Alcohols, Zhigao Shen, Xixian Pan Yisheng Lai, Jiadong Hu, Xiaolong Wan, Xiaoge Li, Hui Zhang, Weiqing Xie*, Chem. Sci. 2015, 6, 6986–6990.
9. Total Synthesis of (-)-Conolutinine, Xiangyang Feng, Guangde Jiang, Zilei Xia, Jiadong Hu, Xiaolong Wan, Jin-Ming Gao, Yisheng Lai*, Weiqing Xie*, Org. Lett. 2015, 17, 4428–4431.
10. Synthesis of Naked Amino-Pyrroloindoline via Direct Aminocyclization of Tryptamine, Zhigao Shen, Zilei Xia, Huijun Zhao, Jiadong Hu, Xiaolong Wan, Yisheng Lai,* Chen Zhu*, Weiqing Xie*, Org. Biomol. Chem., 2015, 13, 5381–5384.
11. Re2O7 catalyzed dienone-phenol rearrangement, Zilei Xia, Jiadong Hu, Zhigao Shen, Qizheng Yao*, Weiqing Xie*, RSC Adv., 2015, 5, 38499–38502.
12. Oxidative Rearrangement of Malondialdehyde: Substrate Scope and Mechanistic Insights, Xin Yu, Zheng Liu, Zilei Xia, Zhigao Shen, Xixian Pan, Hui Zhang* and Weiqing Xie*, RSC Adv., 2014, 4, 53397–53401.
13. Decarboxylative Hydroamination of Propiolic Acids with N-Heterocycles under Transition-Metal-FreeCondition, Xixian Pan, Hui Zhang,* Xin Yu, Xiaolong Wan, Weiqing Xie*, Synlett. 2014, 46, 2057–2064.
14. Highly Asymmetric Bromocyclization of Tryptophol: Unexpected Accelerating Effect of DABCO-derived Bromine Complex, Huan Liu, Guangde Jiang, Xixian Pan, Xiaolong Wan, Yisheng Lai,*, Dawei Ma* and Weiqing Xie*, Org. Lett. 2014, 16, 1908–1911.
15. Highly Enantioselective Bromocyclization of Tryptamines and Its Application in the Synthesis of (-)-Chimonanthine, Weiqing Xie*, Guangde Jiang, Huan Liu, Jiadong Hu, Xixian Pan, Hui Zhang, Xiaolong Wan, Yisheng Lai*, Dawei Ma*, Angew. Chem. Int. Ed. 2013, 52, 12924–12927.
16. Diastereoselective Construction of Continuous All-Carbon Quaternary Centers via Intramolecular Oxidative Coupling Reaction, Weiqing Xie*, Hexiang Wang, Feng Fan, Junshan Tian, Zhiwei Zuo, Weiwei Zi, Kun Gao*, Dawei Ma*, Tetrhedron Lett. 2013, 54, 4392–4396.
17. Intramolecular Oxidative Coupling: Applications in Synthesis of Complex Indole Akaloid Scaffolds, Zhiwei Zuo, Weiwei Zi, Weiqing Xie*, Dawei Ma*, Chin. J. Org. Chem. 2013, 33, 869–876.
18. Asymmetric, Regioselective Bromohydroxylation of 2-Aryl-2-propen-1-ols Catalyzed by Quinine-Derived Catalysts, Ye Zhang, Hui Xing, Weiqing Xie*, Xiaolong Wan, Yisheng Lai*, Dawei Ma*, Adv. Synth. Catal. 2013, 355, 68–72.
19. Cascade annulation of malonic diamides: a concise synthesis of polycyclic pyrroloindolines, Feng Fan, Weiqing Xie*, Dawei Ma*, Chem. Commun., 2012, 48, 7571–7573.
20. Construction of Polycyclic Spiroindolines via an Intramolecular Oxidative Coupling/Cyclization Cascade Reaction Process, Feng Fan, Weiqing Xie*, Dawei Ma*, Org. Lett. 2012, 14, 1405–1407.
六、联系方式
通讯地址:必赢线路检测3003化学与药学院
邮编:712100
邮箱:xiewq@nwafu.edu.cn; xiewqsioc@aliyun.com
课题组主页:http://www.groupxie.com/